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Richard Delorme is head of Child and Adolescent Psychiatry at the Robert Debré University Hospital, Paris, France and professor of Child Psychiatry at the Paris Diderot University (France). He obtained his M.D. at the medical school of Paris Diderot University in 1999 and acquired experience in clinics for child and adolescent neuropsychiatric patients exhibiting a broad range of CNS defects. He is particularly interested in Autism Spectrum Disorders (ASD) and Anxiety Disorders (especially Obsessive Compulsive Disorder, OCD). Richard Delorme is also involved in several research programs and specifically in the search for vulnerability genes associated to developmental disorders such as ASD and OCD. He obtained his Ph.D. with a thesis entitled "Vulnerability Genes in OCD" at the University of Paris XII in 2005. He performed his post-doctorate in the laboratory of Human Genetics and Cognitive Functions directed by Thomas Bourgeron at the Institut Pasteur, Paris, France. He has published over 60 articles in international peer-reviewed journals.

Publications

2016

Bucci, M.P., Stordeur, C., Acquaviva, E., Peyre, H., & Delorme, R. (2016). Postural Instability in Children with ADHD Is Improved by Methylphenidate. Frontiers in Neuroscience, 10, 163.

Darville, H., Poulet, A., Rodet-Amsellem, F., Chatrousse, L., Pernelle, J., Boissart, C., ... Benchoua, A. (2016). Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome. EBioMedicine, (Epub ahead of print).

Forgeot d'Arc, B., Delorme, R., Zalla. T., Lefebvre, A., Amsellem, F., Moukawane, S., ... Ramus, F. (2016). Gaze direction detection in autism spectrum disorder. Autism,  (Epub ahead of print).

Forgeot d'Arc B, Ramus F, Lefebvre A, Brottier D, Zalla T, Moukawane S, ... Delorme R. (2016). Atypical Social Judgment and Sensitivity to Perceptual Cues in Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 46, 1574-1581.

Katz, J., d'Albis, M.A., Boisgontier, J., Poupon, C., Mangin, J.F., Guevara, P., ...  Houenou, J. (2016). Similar white matter but opposite grey matter changes in schizophrenia and high-functioning autism. Acta Psychiatrica Scandinavica, 134, 31-39.

Mercati, O., Huguet, G., Danckaert, A., André-Leroux, G., Maruani, A., Bellinzoni, M., ... Bourgeron, T. (2016). CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders. Molecular Psychiatry, (Epub ahead of print).

Martinerie, L., Le Heuzey, M.F., Delorme, R., Carel, J.C., & Bargiacchi, A. (2016). [Assessment and management of gender dysphoria in children and adolescents]. Archives de pédiatrie, 23, 668-673.

Mosca-Boidron, A.L., Gueneau, L., Huguet, G., Goldenberg, A., Henry, C., Gigot, N., ... Bourgeron, T. (2016). A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability. European Journal of Human Genetics, 24, 838-843.

Peyre, H., Hoertel, N., Rivollier, F., Landman, B., McMahon, K., Chevance, A., ... Limosin, F. (2016). Latent class analysis of the feared situations of social anxiety disorder: A population-based study. Depression and Anxiety, (Epub ahead of print).

Pilorge, M., Fassier, C., Le Corronc, H., Potey, A., Bai, J., De Gois, S., ... Betancur, C. (2016). Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism. Molecular Psychiatry, 21, 936-945.

Torrico, B., Chiocchetti, A.G., Bacchelli, E., Trabetti, E., Hervás, A., Franke, B., ... Toma, C. (2016). Lack of replication of previous autism spectrum disorder GWAS hits in European populations. Autism Research, (Epub ahead of print).

2015

Bennabi, M., Delorme, R., Oliveira, J., Fortier, C., Lajnef, M., Boukouaci, W., ... Tamouza, R. (2015). Dectin-1 Polymorphism: A Genetic Disease Specifier in Autism Spectrum Disorders? PLoS One, 10, e0137339.

Maruani, A., Huguet, G., Beggiato, A., ElMaleh, M., Toro, R., Leblond, C.S., ... Delorme, R. (2015). 11q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures. American Journal of Medical Genetics. Part A, 167, 3019-3030.

Peyret, E., & Delorme, R. (2015). [Cannabis use among children and adolescents: impacts and consequences]. Bulletin de l'Académie nationale de médecine, 198, 579-588.

Rivollier, F., Peyre, H., Hoertel, N., Blanco, C., Limosin, F., & Delorme, R. (2015). Sex differences in DSM-IV posttraumatic stress disorder symptoms expression using item response theory: A population-based study. Journal of Affective Disorders, 187, 211-217.

Septier, M., & Delorme, R. (2015). [Adolescent behavioral disorders]. La Revue du Praticien, 65, 537-544.

Septier, M., & Delorme, R. (2015). [Etiologic factors of adolescent behavioral disorders]. La Revue du Praticien, 65, 535-536.

Stordeur, C., Acquaviva, E., Galdon, L., Mercier, J.C., Titomanlio, L., & Delorme, R. (2015). [Suicide attempts in children under 12 years of age]. Archives de pédiatrie, 22, 255-299.

Tabet, A.C., Verloes, A., Pilorge, M., Delaby, E., Delorme, R., Nygren, G., ... Betancur, C. (2015). Complex nature of apparently balanced chromosomal rearrangements in patients with autism spectrum disorder. Molecular Autism, 6, 19.

Yu, D., Mathews, C. A., Scharf, J. M., Neale, B. M., Davis, L. K., Gamazon, E. R., . . . Pauls, D. L. (2015). Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. American Journal of Psychiatry, 172, 82-93.

2014

Bange, F., Le Heuzey, M.F., Acquaviva, E., Delorme, R., & Mouren, M.C. (2014). [Cardiovascular risks and management during Attention Deficit Hyperactivity Disorder treatment with methylphenidate]. Archives de Pédiatrie, 21, 108-112.

Guilmatre, A., Huguet, G., Delorme, R., & Bourgeron, T. (2014). The emerging role of SHANK genes in neuropsychiatric disorders. Developmental Neurobiology, 74, 113-122.

Hadley, D., Wu, Z.L., Kao, C., Kini, A., Mohamed-Hadley, A., Thomas, K., … Hakonarson, H. (2014). The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism. Nature Communications, 5, 4074.

Huguet, G., Nava, C., Lemiere, N., Patin, E., Laval, G., Ey, E., . . . Bourgeron, T. (2014). Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders. PLoS One, 9, e88600.

Karayannis, T., Au, E., Patel, J. C., Kruglikov, I., Markx, S., Delorme, R., . . . Fishell, G. (2014). Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature, 511, 236-240.

Leblond, C. S., Nava, C., Polge, A., Gauthier, J., Huguet, G., Lumbroso, S., . . . Bourgeron, T. (2014). Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments. PLoS Genet, 10, e1004580.

McGrath, L. M., Yu, D., Marshall, C., Davis, L. K., Thiruvahindrapuram, B., Li, B., . . . Scharf, J. M. (2014). Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 910-919.

Pagan, C., Delorme, R., Callebert, J., Goubran-Botros, H., Amsellem, F., Drouot, X., . . . Launay, J. M. (2014). The serotonin-N-acetylserotonin-melatonin pathway as a biomarker for autism spectrum disorders. Translational Psychiatry, 4, e479.

Peyre, H., Hoertel, N., Cortese, S., Acquaviva, E., De Maricourt, P., Limosin, F., & Delorme, R. (2014). Attention-deficit/hyperactivity disorder symptom expression: a comparison of individual age at onset using item response theory. Journal of Clinical Psychiatry, 75, 386-392.

Peyre, H., Hoertel, N., Hatteea, H., Limosin, F., Dubuc, C., & Delorme, R. (2014). Adulthood self-reported cardiovascular risk and ADHD medications: results from the 2004-2005 National Epidemiologic Survey on Alcohol and Related Conditions. Journal of Clinical Psychiatry, 75, 181-182.

Pinto, D., Delaby, E., Merico, D., Barbosa, M., Merikangas, A., Klei, L., . . . Scherer, S. W. (2014). Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. American Journal of Human Genetics, 94, 677-694.

2013

Boissart, C., Poulet, A., Georges, P., Darville, H., Julita, E., Delorme, R., ... Benchoua, A. (2013). Differentiation from human pluripotent stem cells of cortical neurons of the superficial layers amenable to psychiatric disease modeling and high-throughput drug screening. Translational Psychiatry, 3, e294.

Daprati, E., Nico, D., Delorme, R., Leboyer, M., & Zalla, T. (2013). Memory for past events: movement and action chains in high-functioning autism spectrum disorders. Experimental Brain Research, 226, 325-334.

Davis, L.K., Yu, D., Keenan, C.L., Gamazon, E.R., Konkashbaev, A.I., Derks, E.M., ... Sharf, J.M. (2013). Partitioning the heritability of tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PloS Genetics, 9, e1003864.

Delorme, R., Ey, E., Toro, R., Leboyer, M., Gillberg, C., & Bourgeron, T. (2013). Progress toward treatments for synaptic defects in autism. Nature Medicine, 19, 685-694.

Joncquel-Chevalier Curt, M., Cheillan, D., Briand, G., Salomons, G.S., Mention-Mulliez, K., Dobbelaere, D., ... Vamecq, J. (2013). Creatine and guanidinoacetate reference values in a French population. Molecular Genetics and Metabolism, 110, 263-267.

Ozomaro, U., Cai, G., Kajiwara, Y., Yoon, S., Makarov, V., Delorme, R., ... Grice, D.E. (2013). Characterization of SLITRK1 Variation in Obsessive-Compulsive Disorder. PloS One, 8, e70376.

Pagan, C., Delorme, R., Launay, J.M., & Bourgeron, T. (2013). Alterations of the Serotonin-Melatonin Pathway in Autism Spectrum Disorders: Biological Evidence and Clinical Consequences. In C., Powell & L.M., Monteggia (Eds.), The Autisms: Molecules to Model Systems. New York: Oxford University Press.

Peyre, H., Hoertel, N., Cortese, S., Acquaviva, E., Limosin, F., & Delorme, R. (2013). Long-term effects of ADHD medication on adult height: results from the NESARC. Journal of Clinical Psychiatry, 74, 1123-1124.

Scheid, I., Maruani, A., Huguet, G., Leblond, C.S., Nygren, G., Anckarsäter, H., ... Delorme, R. (2013). Heterozygous FA2H mutations in autism spectrum disorders. BMC Medical Genetics, 14, 124.

Scott, J., Fowler, D., McGorry, P., Birchwood, M., Killackey, E., Christensen, H., ... Hickie, I. (2013). Adolescents and young adults who are not in employment, education, or training. BMJ, 347, f5270.

Stewart, S.E., Yu, D., Scharf, J.M., Neale, B.M., Fagerness, J.A., Mathews, C.A., ... Pauls, D.L. (2013). Genome-wide association study of obsessive-compulsive disorder. Molecular Psychiatry, 18, 788-798.

Stewart, S.E., Mayerfeld, C., Arnold, P.D., Crane, J.R., O'Dushlaine, C., Fagerness, J.A., ... Mathews, C.A. (2013). Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 162, 367-379.

2012

Anney, R., Klei, L., Pinto, D., Almeida, J., Bacchelli, E., Baird, G., … Devlin, B. (2012). Individual common variants exert weak effects on the risk for autism spectrum disorders. Human Molecular Genetics, 21, 4781-4792.

Casey, J.P., Magalhaes, T., Conroy, J.M., Regan, R., Shah, N., Anney, R., … Ennis, S. (2012). A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Human Genetics, 131, 565-579.

Chaste, P., Betancur, C., Gérard-Blanluet, M., Bargiacchi, A., Kuzbari, S., Drunat, S., … Delorme, R. (2012). High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters. Molecular Autism, 3, 5.

Cheillan, D., Curt, M.J., Briand, G., Salomons, G.S., Mention-Mulliez, K., Dobbelaere, D., … Vamecq, J. (2012). Screening for primary creatine deficiencies in French patients with unexplained neurological symptoms. Orphanet Journal of Rare Diseases, 7, 96.

Cortese, S., Azoulay, R., Castellanos, F.X., Chalard, F., Lecendreux, M., Chechin, D., … Konofal, E. (2012). Brain iron levels in attention-deficit/hyperactivity disorder: a pilot MRI study. World Journal of Biological Psychiatry, 13, 223-231.

Leblond, C.S., Heinrich, J., Delorme, R., Proepper, C., Betancur, C., Huguet, G., … Bourgeron, T. (2012). Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genetics, 8, e1002521.

Mouren, M.C., Bourgeron, T., & Delorme, R. (2012). Common and Rare Genetic Variants as Risk Factors for Autism Spectrum Disorders. In E.Garralda (Ed.), The International Association for Child & Adolescent Psychiatry and Allied Professions book series.

Nava, C., Lamari, F., Héron, D., Mignot, C., Rastetter, A., Keren, B., … Depienne, C. (2012). Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE. Translational Psychiatry, 2, e179.

Peyre, H., & Delorme, R. (2012). A case of severe hyperthermia after administration of methylphenidate. Journal of Clinical Psychopharmacology, 32, 299-300.

Sato, D., Lionel, A.C., Leblond, C.S., Prasad, A., Pinto, D., Walker, S., … Scherer, S.W. (2012). SHANK1 Deletions in Males with Autism Spectrum Disorder. American Journal of Human Genetics, 90, 879-887.

Tabet, A.C., Pilorge, M., Delorme, R., Amsellem, F., Pinard, J.M., Leboyer, M., … Betancur, C. (2012). Autism multiplex family with 16p11.2p12.2 microduplication syndrome in monozygotic twins and distal 16p11.2 deletion in their brother. European Journal of Human Genetics, 20, 540-546.

2011

Anney, R.J., Kenny, E.M., O'Dushlaine, C., Yaspan, B.L., Parkhomenka, E., Buxbaum, J.D. … Gallagher, L. (2011). Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders. European Journal of Human Genetics, 19, 1082-1089.

Chaste, P., Clement, N., Botros, H.G., Guillaume, J.L., Konyukh, M., Pagan, C., … Bourgeron, T. (2011). Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders. Journal of Pineal Research, 51, 394-399.

Konyukh, M., Delorme, R., Chaste, P., Leblond, C., Lemière, N., Nygren, G., … Bourgeron, T. (2011). Variations of the candidate SEZ6L2 gene on Chromosome 16p11.2 in patients with autism spectrum disorders and in human populations. PLoS One, 6, e17289.

Pagan, C., Botros, H.G., Poirier, K., Dumaine, A., Jamain, S., Moreno, S., … Bourgeron, T. (2011). Mutation screening of ASMT, the last enzyme of the melatonin pathway, in a large sample of patients with intellectual disability. BMC Medical Genetics, 12, 17.

Sampaio, A.S., Fagerness, J., Crane, J., Leboyer, M., Delorme, R., Pauls, D.L., & Stewart, S.E. (2011). Association between polymorphisms in GRIK2 gene and obsessive-compulsive disorder: a family-based study. CNS Neuroscience & Therapeutics, 17, 141-147.

Schiff, M., Benoist, J.F., Aïssaoui, S., Boespflug-Tanguy, O., Mouren, M.C., de Baulny, H.O., & Delorme, R. (2011). Should metabolic diseases be systematically screened in nonsyndromic autism spectrum disorders? PLoS One, 6, e21932.

2010

Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T.R., … Hallmayer, J. (2010). A genome-wide scan for common alleles affecting risk for autism. Human Molecular Genetics, 19, 4072-4082.

Chaste, P., Clement, N., Mercati, O., Guillaume, J.L., Delorme, R., Botros, H.G., … Bourgeron, T. (2010). Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population. PLoS One, 5, e11495.

Delorme R, Betancur C, Chaste P, Kernéis S, Stopin A, Mouren MC, … Launay, J.M. (2010). Reduced 3-O-methyl-dopa levels in OCD patients and their unaffected parents is associated with the low activity M158 COMT allele. American Journalof Medical Genetics. Part B, Neuropsychiatric Genetics, 153B, 542-548.

Delorme, R., Chaste, P., Scheid, I., Cortese, S., & Mouren, M.C. (2010). Using videotaped vignettes to improve the teaching quality in child and adolescent psychiatry. Medical Teacher, 32, 703-704.

Delorme, R., Betancur, C., Scheid, I., Anckarsäter, H., Chaste, P., Jamain, S., … Bourgeron, T. (2010). Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls. BMC Medical Genetics, 11, 108.

Delorme, R., Moreno-De-Luca, D., Gennetier, A., Maier, W., Chaste, P., Mössner, R., … Betancur, C. (2010). Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorder. BMC Medical Genetics, 11, 100.

Pinto, D., Pagnamenta, A.T., Klei, L., Anney, R., Merico, D., Regan, R., … Betancur, C. (2010). Functional impact of global rare copy number variation in autism spectrum disorders. Nature, 466, 368-372.

Schiff, M., Delorme, R., Benoist, J.F., & Ogier de Baulny, H. (2010). [Should a metabolic work-up be performed in autism?]. Archives de Pédiatrie, 17, 802-803.

Toro, R., Konyukh, M., Delorme, R., Leblond, C., Chaste, P., Fauchereau, F., . . . Bourgeron, T. (2010). Key role for gene dosage and synaptic homeostasis in autism spectrum disorders. Trends in Genetics, 26, 363-372.

2009

Bat-Pitault, F., & Delorme, R. (2009). Aripiprazole and hypertension in adolescents. Journal of Child and Adolescent Psychopharmacology, 19, 601-602.

Bourgeron, T., Leboyer, M., & Delorme, R. (2009). [Autism: more evidence of a genetic cause]. Bulletin de l’Académie Nationale de Médecine, 193, 299-304; discussion 304-295.

Delorme, R., Chaste, P., Mouren-Simeoni, M. C., & Leboyer, M. (2009). Predictors of treatment response in pediatric obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 573; author reply 573-574.

Depienne, C., Moreno-De-Luca, D., Heron, D., Bouteiller, D., Gennetier, A., Delorme, R., . . . Betancur, C. (2009). Screening for genomic rearrangements and methylation abnormalities of the 15q11-q13 region in autism spectrum disorders. Biological Psychiatry, 66, 349-359.

Gong, X., Delorme, R., Fauchereau, F., Durand, C.M., Chaste, P., Betancur, C., … Bourgeron T. (2009). An investigation of ribosomal protein L10 gene in autism spectrum disorders. BMC Medical Genetics, 10, 7.

Hofvander, B., Delorme, R., Chaste, P., Nydén, A., Wentz, E., Ståhlberg, O., . . . Leboyer, M. (2009). Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry, 9, 35.

2008

Gong, X., Bacchelli, E., Blasi, F., Toma, C., Betancur, C., Chaste, P., . . . Bourgeron, T. (2008). Analysis of X chromosome inactivation in autism spectrum disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 147B, 830-835.

Melke, J., Goubran Botros, H., Chaste, P., Betancur, C., Nygren, G., Anckarsäter, H., . . . Bourgeron, T. (2008). Abnormal melatonin synthesis in autism spectrum disorders. Molecular Psychiatry, 13, 90-98.

Stewart, S.E., Rosario, M.C., Baer, L., Carter, A.S., Brown, T.A., Scharf, J.M., … Pauls DL. (2008). Four-factor structure of obsessive-compulsive disorder symptoms in children, adolescents, and adults. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 763-772.

2007

Buxbaum, J.D., Cai, G., Nygren, G., Chaste, P., Delorme, R., Goldsmith, J., . . . Betancur, C. (2007). Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly. BMC Medical Genetics, 8, 68.

Chabane, N., & Delorme, R. (2007). [Obsessive-compulsive disorder in children and adolescents]. La Revue du Praticien, 57, 45-51.

Delorme, R., Goussé, V., Roy, I., Trandafir, A., Mathieu, F., Mouren-Siméoni, M.C., … Leboyer, M. (2007). Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorder. European Psychiatry, 22, 32-38.

Durand, C.M., Betancur, C., Boeckers, T.M., Bockmann, J., Chaste, P., Fauchereau, F., … Bourgeron, T. (2007). Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nature Genetics, 39, 25-27.

Stewart, S.E., Fagerness, J.A., Platko, J., Smoller, J.W., Scharf, J M., Illmann, C., … Pauls, D.L. (2007). Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 144B, 1027-1033.

Stewart, S.E., Platko, J., Fagerness, J., Birns, J., Jenike, E., Smoller, J.W., … Pauls, D.L. (2007). A genetic family-based association study of OLIG2 in obsessive-compulsive disorder. Archives of General Psychiatry, 64, 209-214.

2006

Delorme, R., Bille, A., Betancur, C., Mathieu, F., Chabane, N., Mouren-Simeoni, M.C., & Leboyer, M. (2006). Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents: a prospective follow-up study. BMC Psychiatry, 6, 1.

Delorme, R., Durand, C.M., Betancur, C., Wagner, M., Ruhrmann, S., Grabe, H.J., . . . Malafosse, A. (2006). No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects. Biological Psychiatry, 60, 202-203.

Durand, C.M., Kappeler, C., Betancur, C., Delorme, R., Quach, H., Goubran-Botros, H., . . . Bourgeron, T. (2006). Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 141B, 67-70.Mouren, M.C., & Delorme, R. (2006). [School phobia or school refusal: controversial concepts]. Bulletin de l’Académie Nationale de Médecine, 190, 1629-1639.

2005

Chabane, N., Delorme, R., Millet, B., Mouren, M.C., Leboyer, M., & Pauls, D. (2005). Early-onset obsessive-compulsive disorder: a subgroup with a specific clinical and familial pattern? Journal of Child Psychology and Psychiatry, 46, 881-887.

Delorme, R., Golmard, J.L., Chabane, N., Millet, B., Krebs, M.O., Mouren-Simeoni, M.C., & Leboyer, M. (2005). Admixture analysis of age at onset in obsessive-compulsive disorder. Psychological Medicine, 35, 237-243.

Delorme, R., Betancur, C., Wagner, M., Krebs, M.O., Gorwood, P., Pearl, P., … Bourgeron, T. (2005). Support for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorder. Molecular Psychiatry, 10, 1059-1061.

Delorme, R., Betancur, C., Callebert, J., Chabane, N., Laplanche, J.L., Mouren-Simeoni, M.C., … Leboyer, M. (2005). Platelet serotonergic markers as endophenotypes for obsessive-compulsive disorder. Neuropsychopharmacology, 30, 1539-1547.

Goussé V, Delorme R, Chabane N, Perez-Diaz F, Flavie M, Mouren-Siméoni MC, Leboyer M. (2005). [Is age at onset associated with executive dysfunction in obsessive-compulsive disorder?]. L’Encéphale, 31, 666-671.

2004

Chabane, N., Millet, B., Delorme, R., Lichtermann, D., Mathieu, F., Laplanche, J.L., … Leboyer, M. (2004). Lack of evidence for association between serotonin transporter gene (5-HTTLPR) and obsessive-compulsive disorder by case control and family association study in humans. Neuroscience Letters, 363, 154-156.

Delorme, R., Krebs, M.O., Chabane, N., Roy, I., Millet, B., Mouren-Simeoni, M.C., … Leboyer, M. (2004). Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder. Neuroreport, 15, 699-702.

Henrichsen, C.N., Delorme, R., Boucherie, M., Marelli, D., Baud, P., Bellivier, F., … Dahoun, S. (2004). No association between DUP25 and anxiety disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 128B, 80-83.

2003

Millet, B., Chabane, N., Delorme, R., Leboyer, M., Leroy, S., Poirier, M.F., … Krebs, M.O. (2003). Association between the dopamine receptor D4 (DRD4) gene and obsessive-compulsive disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 116B, 55-59.

 

 

 

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Richard Delorme

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